Researchers have isolated a protein in fatty food which is significant in the metastasizing of cancer in the body. (Science Daily: Cancer spread is increased by a high fat diet, ground-breaking evidence shows)
That shows one immediate advantage in poverty since greasy fast food is the worst and also the most expensive so none of that hog slop ever comes near here.
New research shows that the metastatic process (cancer spread) is enhanced by fat intake. Mice given a high fat diet, including palmitic acid (a major component of palm oil which is found in lots of household products) developed the most aggressive cancer spread. The study identifies for the first time a protein called CD36 which has an essential role in cancer spreading.
It seems the protein is a trigger for metastasis but it's also a marker to identify it.
"Although we have not yet tested this in all tumour types, we can state that CD36 is a general marker of metastatic cells, the first I know of that is generally specific to metastasis," says Professor Benitah, Head of the Stem Cell and Cancer Lab at IRB Barcelona.
"We expect this study to have a big impact on the scientific community and to further advances in metastasis research, and we hope to be able to validate the potential of CD36 as an anti-metastasis treatment. Things like this don't happen every day."
The researchers are now developing new antibody-based therapeutics against CD36 that could potentially be suitable to treat a range of cancers in patients in the future.
That shows one immediate advantage in poverty since greasy fast food is the worst and also the most expensive so none of that hog slop ever comes near here.
New research shows that the metastatic process (cancer spread) is enhanced by fat intake. Mice given a high fat diet, including palmitic acid (a major component of palm oil which is found in lots of household products) developed the most aggressive cancer spread. The study identifies for the first time a protein called CD36 which has an essential role in cancer spreading.
...
Professor Benitah's team found CD36 was present on metastatic cancer cells from patients with a range of different tumours including oral tumours, melanoma skin cancer, ovarian, bladder, lung and breast cancer. To confirm its essential role in cancer spread, they added CD36 to non-metastatic cancer cells which then caused the cells to become metastatic.
- Science Daily
It seems the protein is a trigger for metastasis but it's also a marker to identify it.
"Although we have not yet tested this in all tumour types, we can state that CD36 is a general marker of metastatic cells, the first I know of that is generally specific to metastasis," says Professor Benitah, Head of the Stem Cell and Cancer Lab at IRB Barcelona.
"We expect this study to have a big impact on the scientific community and to further advances in metastasis research, and we hope to be able to validate the potential of CD36 as an anti-metastasis treatment. Things like this don't happen every day."
- Science Daily
The point of this exercise is not doom and gloom. We're not finished yet so here's the beauty part.
Using mice with human oral cancer, the researchers were next able to show that blocking CD36 completely prevented metastasis. In mice with cancer cells that had already metastasised, CD36 blocking antibodies led to the complete removal of metastases in 20% of the mice, whilst in the others it caused a dramatic reduction of 80-90% of metastases and reduced the size. Importantly, this was all achieved with no serious side effects.
The researchers are now developing new antibody-based therapeutics against CD36 that could potentially be suitable to treat a range of cancers in patients in the future.
- Science Daily
Do we find the cool stuff or what. Who loves you, baby?
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