Friday, January 20, 2017

Increased Risk of Birth Defects from Anti-Depressants - Science

Probably most of the Thalidomide babies have died by now but some recall what the Thalidomide did to them in the early Sixties.  That's germane because it was originally prescribed as a sedative.  (WIKI:  Thalidomide)

In the current research, it's revealed the risk of birth defects is doubled with the use of anti-depressants now.  (Science Daily:  New data show heightened risk of birth defects with antidepressants prescribed during pregnancy)

The risk -- 6 to 10 %, versus 3 to 5 % in women who do not take the drugs -- is high enough to merit caution in their use, especially since, in most cases, they are only marginally effective, the study says.

- SD

As I said, the risk doubles.

"Given that an increasing number of women are diagnosed with depression during pregnancy, (the new) results have direct implications on their clinical management," the study concludes. "This is even more important given that the effectiveness of antidepressants during pregnancy for the treatment of the majority of cases of depression (mild to moderate depression) have been shown to be marginal. "Hence, the need for caution with antidepressant use during pregnancy is warranted and alternative non-drug options should be considered."

- SD

Read the article for the full spiel but I'm sure you get it already.


Unknown if the second part of this is good news or more of the same since researchers have discovered a new way to chemically deal with depression, etc.  (Science Daily:  New avenue for anti-depressant therapy discovered)


Researchers used virus tools to find out where in the brain the JNK inhibitor acted to improve mood. They found out the molecule acts to alleviate anxiety and depression by controlling newly born nerve cells in the hippocampus. The image, taken at the Cell Imaging Core, shows these new born cells in the hippocampus, the region of the brain that controls emotions.

Credit: Turku Centre for Biotechnology

- SD

In some odd sense, they can almost watch an emotion happen.


I'm not going to continue with the article as I'm heavily-biased against such drugs after being prescribed many of them and discovered minimal efficacy with any of them.  The article is presented for the balance since Ithaka does not believe in telling you what to think and would not respect you if you expected that.  The resources are before you and make of them what you will but, here at the Rockhouse, any risk of a birth defect is never, ever acceptable.

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